As all of Manhattan is transformed into an island of Spider-Men, the city is quarantined! As Spider-Man battles the problem at its source, Marvel's other heroes take on the task of calming a city of spider-powered citizens - and battling an army of spider-powered criminals.

COLLECTING: SPIDER-ISLAND: THe AMAZING SPIDER-GIRL 1-3; SPIDER-ISLAND: CLOAK & DAGGER1-3;SPIDER-ISLAND: DEADLY HANDS OF KUNG FU 1-3;HERC 7-8; SPIDER-ISLAND: AVENGERS 1; SPIDER-ISLAND: SPIDER-WOMAN 1; HEROES FOR HIRE 12; BLACK PANTHER 524; SPIDER-ISLAND: HEROES FOR HIRE; SPIDER-ISLAND SPOTLIGHT